Peter St. George-Hyslop, MD, PhD, FRSC, FRCPC

Team Lead: Genetics


Professor, Department of Medicine
University of Toronto

Investigator, Howard Hughes Medical Institute



Center for Research in Neurodegenerative Disease


Contact Dr. St. George-Hyslop


Dr. Peter St.George-Hyslop received his M.D. from the Faculty of Medicine, University of Ottawa, and an F.R.C.P.(C) in internal medicine and in neurology from the Royal College of Physicians of Canada. He conducted postdoctoral research at the University of Toronto and at Harvard Medical School and was appointed Instructor in Neurology and Genetics at Harvard University and was an assistant physician in the Department of Neurology and the Department of Genetics at Massachusetts General Hospital. In 2003 he assumed his current position as Professor of Medicine at the University of Toronto.


Dr. St George-Hyslop’s research on the genetics of Alzheimer's disease has made a significant impact on the field of molecular and biochemical research. In addition to his work on Alzheimer disease, Dr. St George-Hyslop has made major contributions to the understanding of several other genetic diseases, such as Parkinson's, motor neuron disease, and Creutzfeldt-Jakob/mad cow disease.


Dr. St George-Hyslop has published more than 200 papers in leading peer-reviewed journals, such as Nature, Nature Genetics, Nature Medicine, and Science; he is one of the most cited authors in the field of Alzheimer disease research. His research has earned him numerous awards and prizes. His honors include the Francis A. McNaughton Prize from the Canadian Neurologic Society and the Award for Medical Research from the Metropolitan Life Foundation. He was selected as a Medical Research Council of Canada (Canadian Institutes of Health Research) Scholar in 1991 and as Distinguished Scientist in 2000. He received the Gold Medal in Medicine from the Royal College of Physicians of Canada in 1994 and the Michael Smith Award from the Canadian Institutes of Health Research in 1997. In 1995, he became a member of the American Society for Clinical Investigation, and he is a fellow of the Royal Society of Canada. In 2004 he was awarded the Oon Prize in Medicine from the University of Cambridge, and in 2007 he was elected as a foreign member to the Institute of Medicine of the National Academies.